Document Type : Original Article
Researcher
i dont have
Ministerial Ethics Committee
This study aims to investigate the effect of a single session of resistance exercise combined with fresh pomegranate juice consumption on metabolic indices, including insulin resistance, HbA1c, and the triglyceride–glucose (TyG) index in individuals with type 2 diabetes. Type 2 diabetes, due to its high prevalence and association with obesity and sedentary lifestyle, is one of the major global health challenges. Evidence indicates that resistance training can improve insulin sensitivity, while pomegranate juice—rich in polyphenols, antioxidants, and anti-inflammatory compounds—may have beneficial effects on glucose control and lipid profile.
The present research is a semi-experimental study using a randomized crossover design. Participants will include 20 men aged 40–65 years with non-insulin-dependent type 2 diabetes. Each subject will complete two sessions separated by a seven-day washout period: (1) resistance exercise plus fresh pomegranate juice and (2) resistance exercise plus placebo. The resistance training protocol includes six multi-joint exercises performed at 70% of one-repetition maximum (1RM), three sets of 8–10 repetitions each. Fresh pomegranate juice, prepared via cold-press extraction, will be consumed in a 300-ml dose. Blood samples will be collected before and 24 hours after exercise, and HOMA-IR, TyG, HbA1c, and lipid profile will be measured using the ELISA method.
The findings of this research may provide a better understanding of the short-term metabolic responses to the combined effects of resistance exercise and pomegranate juice, offering a simple, natural, safe, and low-cost complementary intervention for the initial management of type 2 diabetes.