Document Type : Original Article
Researchers
1 studentExercise Physiology, Faculty of Physical Education and Sport Sciences, Allameh Tabatabaei University, Tehran, Iran
2 Exercise Physiology, ,Faculty of Physical Education and Sport Sciences,, Allameh Tabatabaei University, Tehran, Iran
Ministerial Ethics Committee
This quasi-experimental and applied study follows a pre-test and post-test design with two experimental groups and one control group. The statistical population consists of women aged 20 to 30 years, residing in Isfahan, with a body mass index (BMI) between 20 and 25, and suffering from acne. A total of 30 volunteers will be randomly assigned to the training and control groups. Inclusion criteria include not using immunosuppressive drugs, having no chronic diseases, not smoking, and not engaging in regular exercise in the past six months. The independent variable is an eight-week resistance training program, while dependent variables include monocyte and neutrophil counts, neutrophil-to-lymphocyte ratio, TLR-2 gene expression, and interleukin-8 levels. Data collection tools include questionnaires on sleep quality, acne severity, personal health information, and laboratory equipment such as calipers, standard measuring tape, a scale, and a stadiometer. After initial registration and screening, blood samples will be collected on days 7 to 9 of the menstrual cycle, 48 hours before the start of the training program, and 48 hours after the last session. The training protocol consists of eight weeks of resistance exercises, three sessions per week, each lasting 60 minutes. Each session includes a warm-up, seven resistance exercises (such as bench press, leg press, knee and elbow movements), and a cool-down. Training intensity starts at 55% of one-rep max and increases every two weeks, with 45 to 60 seconds of rest between sets and 90 seconds between stations. Dietary habits and sleep patterns will also be controlled as confounding factors.