Document Type : Original Article

Researcher

nadarm

IR/ethics.2024.78415.1005

Ministerial Ethics Committee

Type 2 diabetes is one of the most common metabolic disorders worldwide. The incidence and prevalence of type 2 diabetes is still increasing in many parts of the world, which is related to the increase in the prevalence of obesity and sedentary lifestyle. Chronic low-grade inflammation as a contributing factor to type 2 diabetes. The NLRP3 inflammasome plays an important role in the development of dilbet. NLRP3 responds to a variety of stimuli such as toxins, pathogens, metabolites, crystalline materials, acid, nucleotides, and ATP and consequently activates caspase-1, targeting the activated caspase to the plasma membrane and leading to cell pore and is lysed and which starts the programmed death process which is called pyroptosis. The data predict a worrisome future for type 2 diabetes.

Non-pharmacological interventions increase physical activity and regular exercise at high intensities and improve average health and quality of life in people with obesity and its related complications. With the widespread increase, people are turning more and more to alternative treatments in order to control their disease, despite many conventional treatments, which are dietary supplements, which are complementary and alternative treatments that are in the form of diseases. The general public is used, among other things